Citrullus colocynthis fruits are usually recognized for its wide range of medicinal uses as well as pharmaceutical and nutraceutical potential. Indeed, if you will imagine a watermelon vine bearing a small, hard fruit with a bitter pulp, you. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while. Citrullus colocynthis supplement health benefits, dosage. The seeds are claimed to be nutritional but the pulp and outer skin of the gourd contains a highly poisonous constituent called colocynthin.
Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. Colocynthis citrullus, but is now classified as citrullus colocynthis. There have been reports of death following ingestion of just 112. New state records for citrullus, cucumis, and cucurbita cucurbitaceae outside of cultivation in the usa. Round, yellow fruit with green spots and poisonous pulp, which fits the elisha story 2 kings 4. It is known by various names such as bitter cucumber, pumpkin seeds, egusi melon, vine of sodom plant, wild gourd, bitter apple, colocynth or desert gourd. A unique symptom guiding use of berberis vulgaris is pain in left kidney that radiates down the ureter and into the urinary bladder. It is especially suitable for irritable persons easily angered, and ill effects therefrom. The invention includes a process combining component a. The rdna distribution has also been investigated in c.
Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia it resembles a common watermelon vine, but bears small, hard fruits with a bitter pulp. Colocynthis 30c by boiron helps with my sciatic pain when some other remedies like ruta, arnica etc. Citrullus colocynthis synonyms, citrullus colocynthis pronunciation, citrullus colocynthis translation, english dictionary definition of citrullus colocynthis. Antibacterial screening of citrullus colocynthis request pdf. Schrad is a valuable cucurbit plant, widely distributed in the desert areas of the world. It has also been referred by its earlier name citrullus vulgaris. Stimulant laxatives can decrease potassium levels in the body. It is very good for all kinds of painful conditions including. Colocynth definition of colocynth by the free dictionary. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon c.
Gray scale images were captured for each color channel and then merged. Berberis vulgaris and hedeoma pulegioides for kidney stones of left side. The article also presents some of the functions of the chemicals present and attempt to emphasize and create an awareness of the great potential of citrullus colocynthis as a source of novel. It is especially suitable for irritable persons easily. Page designed through the cooperative efforts of interagency itis teams. Evaluation and characterisation of citrullus colocynthis l. There have been reports of death following ingestion of just. Citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally.
While every effort has been made to provide the most reliable and uptodate information available, ultimate legal requirements with respect to species are contained in. An overview of chemical composition and biomedical potentials article pdf available in asian journal of plant sciences 97. Effects of alkaloid rich extract of citrullus colocynthis. Learn more about colocynth uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain colocynth. Colocynthis is available in a multidose tube, with approx.
Perennial trailing herb with somewhat woody tuberous rootstock. Effect of citrullus colocynthis on hair growth in albino rats. It was banned by the food and drug administration fda in 1991. Colocynthis is native to turkey but is cultivated in many dry, hot semidesert areas around the world. The letters hpus indicate that this ingredient is officially included in the homeopathic pharmacop. This page was last edited on 23 december 2019, at 06. Colocynth citrullus colocynthis uses, dosage, side effects. Colocynthis definition of colocynthis by medical dictionary. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. Hosted by the usgs core science analytics and synthesis. Uses, side effects, interactions, dosage, and warning. Nontoxic dental care herbal formulation for preventing dental plaque and gingivitis download pdf.
Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins. Low potassium levels can increase the risk of side effects of digoxin lanoxin. Berberis vulgaris is one of the top listed medicines for kidney stones formed on the left side. Citrullus colocynthis an overview sciencedirect topics. However, it is not a legal authority for statutory or regulatory purposes. Often indicated in the transition season when the air is cold, but the sun is still powerful enough to heat the blood. These compounds include elatermidine, glycosides, resin, dihydric alcohol, heltiacontane, citrullin and citrullinic acid.
Citrullus colocynthis was reported in multiple ethnopharmacologic studies from different part of the world as a traditional remedy for a variety of diseases including gastrointestinal, musculoskeletal, neurological, cardiovascular, and respiratory disorders also, diabetes mellitus is known as the most popular traditional indication of c. Homeopathic medicines for kidney stone dissolve them. Egusi seed is botanically known as citrullus colocynthis curcurbita citrullus l. Sep 17, 2019 colocynth is a type of laxative called a stimulant laxative. Colocynthis homoeopathic materia medica by william. Other side effects include convulsions, paralysis, and death. Citrullus colocynthis and citrullus vulgaris both look alike and. Publisher macmillan press year 1992 isbn 0333474945 description excellent and very comprehensive, though it contains a number of silly mistakes. Molecularly imprinted polymer of colocynthin, an effective. Colocynthishomaccord injection solution is a clear, colorless solution. Citrullus, the latin diminutive of citrus, from the appearance of the fruit. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a powerful hepatic stimulant and hydragogue cathartic. Callus induction and plant regeneration from leaf explants of falcaria vulgaris an.
Fraction a and a fraction from citrullus colocynthis designated as fraction b. The present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of extracts and chemicals identified from citrullus colocynthis. Pdf comparative study of amino acid and proximate composition. Introduction world health organization survey indicated that about 7080% of the worlds population rely on nonconventional medicine, mainly of herbal sources, in their primary healthcare. The fruit pulp of colocynth has medicinal properties while the seeds have nutritive qualities. Citrullus colocynthis, pharmacology, constituent, pharmacognosy i. Molecularly imprinted polymer of colocynthin, an effective tool for quality control of citrullus colocynthis extracts. It was always known as a toxic gourd but was turned to as a food in desperate times. Colocynth is a type of laxative called a stimulant laxative. Ramezany f, khanavi m, ardakani mr, sellegren b, eftekhari m, rastegar h, shekarchi m1. It was banned by the food and drug administration in 1991 taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. The wild gourds in the bible were most likely the fruit of the citrullus colocynthis. The board of trustees of the royal botanic gardens, kew.
Chemical constituents and pharmacological effects of. The fruit is an orange sized gourd that contains pulp and seed. Citrullus colocynthis definition of citrullus colocynthis. Antimycobacterial activity of citrullus colocynthis l. Wo2004084852a1 nontoxic dental care herbal formulation for. It is a groundhugging vine which grows abundantly in dry conditions. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Colocynthis homoeopathic materia medica by william boericke. The plant is cultivated in europe for ornamental purposes. Known hazards the plant contains a number of potentially toxic compounds and can be harmful if used in quantity. Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. Low doses of its seeds and fruit can reduce blood glucose levels. Citrullus colocynthis in kew science plants of the world online.
Four patients with colocynth intoxication are presented. I have not used it by itself as a solo remedy for long so its hard to gauge its overall effectiveness. Citrullus colocynthis as the cause of acute rectorrhagia. Develops most of its symptoms in the abdomen and head, causing intense neuralgias. Cytogenetic relationships among citrullus species in. Leafblade elongateovate in outline, distinctly scabridhairy beneath, smooth except on the nerves above, 26110 mm. Higher doses are associated with sideeffects like colonic inflammation and rectal bleeding. All structured data from the file and property namespaces is available under the creative commons cc0 license. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia. The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. Other names abu jahl, alhandal, bitter apple, bitter cucumber.
Request pdf antibacterial screening of citrullus colocynthis crude. Files are available under licenses specified on their description page. Jan 04, 2017 molecularly imprinted polymer of colocynthin, an effective tool for quality control of citrullus colocynthis extracts. Origin and domestication of cucurbitaceae crops new phytologist. These were subjected to analyse the nutrients profile such as crude protein, carbohydrate, lipid, profile of essential amino acids and minerals. Colocynth citrullus colocynthis important information. Colocynthis, bitter apple, bitter cucumber, colocynth. Schrad, which has been used in traditional and ethno medicine of. Dried or minced plants of citrullus colocynthis in doses of 0. Safety evaluation studies of citrullus colocynthis for. Cytogenetic relationships among citrullus species in comparison. Homeopathy a homeopathic remedy used for colic, neuralgia caused by suppressed emotions, gastric pain, headaches accompanied by nausea and vomiting, gout, rheumatic complaints, and vertigo. Persons familiar with the common watermelon vine need no description of the plant which produces colocynth apples.
About europe pmc funders joining europe pmc governance roadmap. The leading symptoms of the remedy include a tendency to pentup emotions, especially anger, restlessness with pain and an aversion to talking, answering or having much contact with people at all. A tendrilbearing old world vine bearing yellowish, greenmottled fruits the size of small lemons. Colocynthis est principalement indique dans les douleurs spasmodiques et crampoides. Jun 14, 2018 citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant. Homeopathy a homeopathic remedy used for colic, neuralgia caused by suppressed emotions, gastric pain, headaches accompanied by nausea and. Minoxidil 2% solution was applied topically and served as the standard.
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